Artikelnummer: E-AB-93063_60μL-ES

ALKBH5 Polyclonal Antibody, 60 μL

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.

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Produktspezifikation

Grundlegende Informationen

Marken: Elabscience

Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Herkunftsort: China

Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:43kDa/44kDa/52kDa

Observed Molecular Weight:40-50KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:43kDa/44kDa/52kDa

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

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Konzentration: 1mg/mL

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Anwendung: WB;IHC

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