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Artikelnummer: E-AB-F1177C_100T×2-ES
FITC Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2], 100 T×2
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: Ice bag
Speicher: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Haltbarkeit: 12 months
Herkunftsort: China
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Concentration:5 μL/Test
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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