- Spezifikation
- Downloads
- Bewertungen
€3.948,00
ADD TO CART
Artikelnummer: AN001210P_1mg-ES
IGFBP-5 Monoclonal Antibody(Detector), 1 mg
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues,which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBPs,including glycosylation,phosphorylation and proteolysis,have been shown to modify the affinities of the binding proteins to IGF. Mouse IGFBP-5 cDNA encodes a 271 amino acid (aa) residue precursor protein with a putative 19 aa residue signal peptide that is processed to generate the 252 aa residue mature protein. Mouse,human and rat IGFBP-5 share 97% identity. IGFBP-5 is expressed by fibroblasts,myoblasts and osteoblasts,making it the predominant IGFBP found in bone extracts. IGFBP-5 has a strong affinity for hydroxyapatite,allowing it to bind to bone cells. When bound to extracelluar matrix,IGFBP-5 is protected from proteolysis and potentiates IGF activity,but when it is soluble,IGFBP-5 is cleaved to a biologically inactive 21 kDa fragment.
- Regulärer Preis
- €3.948,00 EUR
- Verkaufspreis
- €3.948,00 EUR
- Regulärer Preis
-
ADD TO CART
Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Speicher: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
Capacity:
Concentration:1 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:
Purity:
Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:ELISA Detector 0.1-0.4 μg/mL
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Parameterinformationen
Materialien:
Erkennungsbereich:
Testprinzip:
Inter-Lebenslauf:
Intra-Lebenslauf:
Formular:
Konzentration: 1 mg/mL
Reinheit:
Komponente:
Partikelgröße:
Beispiel:
Em:
Erkennungsinstrument:
Testzeit:
Sensibilität:
Synonyme:
Erkennungsziel:
Reaktivität:
Anwendung: ELISA Detector
Spezifität:
Präzision:
Quantitativ/Qualitativ:
Wiederherstellung: