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Artikelnummer: AN005400L_25μL-ES
Ki67 Monoclonal Antibody, 25 μL
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
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Dilution:IHC 1:500-1:1000;IF 1:200-1:400
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Konzentration: 1 mg/mL
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Anwendung: IHC;IF
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