- Spezifikation
- Downloads
- Bewertungen
€607,00
ADD TO CART
Artikelnummer: E-AB-F1024UH_100μg-ES
PE/Cyanine7 Anti-Mouse CD272/BTLA Antibody[PK18.6], 100 μg
CD272, also known as B and T lymphocyte attenuator (BTLA), is an Ig superfamily co-inhitory receptor with structural similarity to programmed cell death 1 (PD-1) and CTLA-4. BTLA is expressed on B cells, T cells, macrophages, dendritic cells, NKT cells, and NK cells. Engagement of BTLA by its ligand herpes virus entry mediator (HVEM) is critical for negatively regulating immune response. The absence of BTLA with HVEM inhibitory interactions leads to increased experimental autoimmune encephalomyelitis severity, enhanced rejection of partially mismatched allografts, an increased CD8+ memory T cell population, increased severity of colitis, and reduced effectiveness of T regulatory cells. BTLA plays an important role in the induction of peripheral tolerance of both CD4+ and CD8+ T cells in vivo. Tolerant T cells have significantly higher expression of BTLA compared with effectors and naïve T cells. BTLA may cooperate with CTLA-4 and PD-1 to control T cell tolerance and autoimmunity. It was reported that BTLA may regulate T cell function by binding to B7-H4, but further studies are needed to confirm. The existence of three distinct BTLA alleles has been reported.
- Regulärer Preis
- €607,00 EUR
- Verkaufspreis
- €607,00 EUR
- Regulärer Preis
-
ADD TO CART
Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: Ice bag
Speicher: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
Capacity:
Concentration:0.2 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:
Purity:
Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Parameterinformationen
Materialien:
Erkennungsbereich:
Testprinzip:
Inter-Lebenslauf:
Intra-Lebenslauf:
Formular:
Konzentration: 0.2 mg/mL
Reinheit:
Komponente:
Partikelgröße:
Beispiel:
Em:
Erkennungsinstrument:
Testzeit:
Sensibilität:
Synonyme:
Erkennungsziel:
Reaktivität:
Anwendung: FCM
Spezifität:
Präzision:
Quantitativ/Qualitativ:
Wiederherstellung: