Artikelnummer: E-AB-93218_120μL-ES

PLN Polyclonal Antibody, 120 μL

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

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Grundlegende Informationen

Marken: Elabscience

Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Herkunftsort: China

Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:6kDa

Observed Molecular Weight:6KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:6kDa

Dilution:WB 1:500-1:2000

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Konzentration: 1mg/mL

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