Artikelnummer: PDEH100994_20μg-ES

Recombinant Human Rad51 protein (His tag), 20 μg

Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

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Grundlegende Informationen

Marken: Elabscience

Versand: This product is provided as lyophilized powder which is shipped with ice packs.

Speicher: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Herkunftsort: China

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Calculated Molecular Weight:37.1 kDa

Observed Molecular Weight:38 kDa

Purity: > 95% as determined by reducing SDS-PAGE.

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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Calculated Molecular Weight:37.1 kDa

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Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

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Reinheit: > 95% as determined by reducing SDS-PAGE.

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Synonyme: HsRAD51;DNA repair protein RAD51 homolog 1;RAD51;hRAD51

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