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Artikelnummer: PKSM041482_20μg-ES
Recombinant Mouse IL-36RA protein(His Tag), 20 μg
Human Interleukin-36 Receptor Antagonist (IL-36RN) is a secreted protein which belongs to the Interleukin 1 cytokine family (IL-1 family). IL-36RN is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. IL-36RN is also detected in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin. IL-36RN is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to Interleukin 1 family member 9 (IL1F9). Dysregulated expression of novel agonistic and antagonistic IL-1 family member ligands can promote cutaneous inflammation, revealing potential novel targets for the treatment of inflammatory skin disorders. Human and mouse IL-36RN share 90% sequence identity.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: This product is provided as lyophilized powder which is shipped with ice packs.
Speicher: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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Herkunftsort: China
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Calculated Molecular Weight:17.8 kDa
Observed Molecular Weight:17-25 kDa
Purity: > 98 % as determined by reducing SDS-PAGE.
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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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Calculated Molecular Weight:17.8 kDa
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Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
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Reinheit: > 98 % as determined by reducing SDS-PAGE.
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Synonyme: EBI;Interleukin;Il1f;Il1h;Il1hy;EBI3;EBV-induced gene 3 protein;Epstein-Barr virus-in duced gene 3 protein;IL-27-A;IL-27B;IL-30;Interleukin-27 subunit alpha;Interleukin-27 subunit beta;Interleukin-30;p28;Fil1d;Il1f5;Il1h3;Il1hy1;IL36RN
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Anwendung: Cell culture
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