Artikelnummer: PKSM041084_10μg-ES

Recombinant Mouse Interleukin-22/IL-22 Protein (mFc Tag), 10 μg

Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.

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Grundlegende Informationen

Marken: Elabscience

Versand: This product is provided as lyophilized powder which is shipped with ice packs.

Speicher: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Herkunftsort: China

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Calculated Molecular Weight:43.8 kDa

Observed Molecular Weight:50-65 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Calculated Molecular Weight:43.8 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Reinheit: > 95 % as determined by reducing SDS-PAGE.

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Synonyme: Interleukin;Cytokine Zcyto;IL-D;TIFIL;Cytokine Zcyto18;IL-10-related T-cell-derived-inducible factor;IL-22a;IL-D110;IL-TIF;Interleukin-22a;TIFa;TIFIL-23;UNQ3099/PRO10096;zcyto18;Interleukin-22;T-cell-derived-inducible;factor(IL-TIF);Interleukin-22a(IL-22a);IL-TIF alpha;IL-10-related;IL-22;Il22a;Iltif;Iltifa;Il22;TIFa

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