Artikelnummer: PKSM041301_50μg-ES

Recombinant Mouse NGAL/Lipocalin-2 Protein (Fc Tag), 50 μg

Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signaling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts.Recent evidence also suggests its role as a biomarker for renal injury and inflammation.

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Grundlegende Informationen

Marken: Elabscience

Versand: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Speicher: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Herkunftsort: China

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Calculated Molecular Weight:48.0 kDa

Observed Molecular Weight:55-60 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:48.0 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Reinheit: > 95 % as determined by reducing SDS-PAGE.

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Synonyme: LCN2;Lipocalin-2;NGAL;Neutrophil gelatinase-associated lipocalin;SV-40-induced 24P3 protein;Siderocalin LCN2;p25

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