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Artikelnummer: PKSM041279_50μg-ES
Recombinant Mouse Serpin A3N Protein (His Tag), 50 μg
Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, and spleen. It is expressed with low levels in bone marrow, kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic lymphocytes, providing a means to disable cellmediated immune responses.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Speicher: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Herkunftsort: China
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Calculated Molecular Weight:45.6 kDa
Observed Molecular Weight:58 kDa
Purity: > 95 % as determined by reducing SDS-PAGE.
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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Calculated Molecular Weight:45.6 kDa
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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
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Synonyme: Serine protease inhibitor A3N;Serpin A3N;Serpina3n;Spi2
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