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Artikelnummer: PKSR030331_100μg-ES
Recombinant Rat IL17RA Protein (His Tag), 100 μg
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor which binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: This product is provided as lyophilized powder which is shipped with ice packs.
Speicher: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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Herkunftsort: China
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Calculated Molecular Weight:34.1 kDa
Observed Molecular Weight:52-58 kDa
Purity: > 95 % as determined by reducing SDS-PAGE.
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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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Calculated Molecular Weight:34.1 kDa
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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
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Synonyme: IMD;MGC;CTLA;CANDF;CDw;IL17RA;CANDF5;CD217;CDw217;IL-17RA;IL17R;IMD51;hIL-17R;CD127;CD217 antigen;CDW127;CTLA8;HIL 17R;hIL17R;I17RA;IL 17 receptor;IL 17 receptor A;IL 17RA;IL17;IL-17 R alpha;IL-17 receptor A;IL17A receptor;IL-17R;IL17R-A;IL17-RA;IL-17R-alpha;IL7RA;ILRA;Interleukin 17 receptor A;Interleukin-17 receptor A;MGC10262; CDw217;Interleukin-17 receptor A
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Anwendung: ELISA
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