- Spezifikation
- Downloads
- Bewertungen
€3.304,00
ADD TO CART
Artikelnummer: PKSR030419_100μg-ES
Recombinant Rat TGFB1/TGF-beta 1 Protein, 100 μg
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
- Regulärer Preis
- €3.304,00 EUR
- Verkaufspreis
- €3.304,00 EUR
- Regulärer Preis
-
ADD TO CART
Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: This product is provided as lyophilized powder which is shipped with ice packs.
Speicher: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Haltbarkeit:
Herkunftsort: China
Technical Specifications
Capacity:
Concentration:
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:12.8 kDa
Observed Molecular Weight:
Purity: > 90 % as determined by reducing SDS-PAGE.
Shelf Life:
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:12.8 kDa
Dilution:
Driving Motor DC motor:
Em:
Ex:
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Flow rate [liquid]:
Parameterinformationen
Materialien:
Erkennungsbereich:
Testprinzip:
Inter-Lebenslauf:
Intra-Lebenslauf:
Formular:
Konzentration:
Reinheit: > 90 % as determined by reducing SDS-PAGE.
Komponente:
Partikelgröße:
Beispiel:
Em:
Erkennungsinstrument:
Testzeit:
Sensibilität:
Synonyme: TGF-beta 1;TGFB;TGFbeta
Erkennungsziel:
Reaktivität:
Anwendung: Cell culture
Spezifität:
Präzision:
Quantitativ/Qualitativ:
Wiederherstellung: