Proteomics & Structural Biology

Comprehensive Insights into Protein Function and Dynamics

Proteins are the molecular engines of life, driving nearly all biological processes. Their diverse functions—enzymatic, structural, regulatory, and signaling—are intricately linked to their three-dimensional structures and dynamic behavior. Proteomics and structural biology aim to unravel the complexity of proteins by studying their expression, purification, interactions, activity, and structure. These insights enable applications ranging from basic biological research to drug development and biotechnological innovations.
What is proteomics?
Proteomics is the large-scale study of proteins, focusing on their structure, function, interactions, and role in biological processes. It aims to understand the proteome, the entire set of proteins expressed by a genome, cell, tissue, or organism.
Why is structural biology important?
Structural biology provides insights into the three-dimensional arrangement of proteins and their dynamics. Understanding protein structures helps explain how they function, interact with other molecules, and can guide drug design and disease research.
How is mass spectrometry used in proteomics?
Mass spectrometry is a powerful tool for identifying and quantifying proteins in complex samples. It helps analyze protein modifications, interactions, and expression levels, advancing disease research and biomarker discovery.