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SKU: E-AB-93063_120μL-ES
ALKBH5 Polyclonal Antibody, 120 μL
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:43kDa/44kDa/52kDa
Observed Molecular Weight:40-50KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:43kDa/44kDa/52kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Features and Capabilities
Application:WB;IHC
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Research Areas:Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Target Synonym:ALKBH5;ABH5;OFOXD;OFOXD1
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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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