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SKU: E-AB-22010_120μL-ES
AMACR Monoclonal Antibody, 120 μL
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:42kDa
Observed Molecular Weight:42kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:42kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:100-1:300
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Application:WB;IHC-p;IF
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Research Areas:Cell Biology;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha-methylacyl-CoA racemase;Amacr;AMACR;AMACRD;CBAS4;EC 5.1.99.4;Macr1;RACE;RM
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Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
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Clonality:Monoclonal
Conjugation:Unconjugated
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