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SKU: E-AB-F1199UE_25μg-ES
APC Anti-Mouse IL-17A Antibody[TC11-18H10.1], 25 μg
IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:Ice bag
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Concentration:0.2 mg/mL
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Application:ICFCM
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Research Areas:Cell Biology;Immunology;Neuroinflammation;Neuroscience
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Target Synonym:CTLA-8;CTLA8;Cytotoxic T-lymphocyte-associated antigen 8;IL-17;IL-17A;Interleukin-17A
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Clonality:Monoclonal
Conjugation:APC
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