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SKU: E-AB-93396_200μL-ES
ATR Polyclonal Antibody, 200 μL
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:294kDa/297kDa/301kDa
Observed Molecular Weight:301kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:294kDa/297kDa/301kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human
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Target Synonym:ATR;FCTCS;FRP1;MEC1;SCKL;SCKL1
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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