SKU: AN002530P_25μg-ES

BAFF R/TNFRSF13C Monoclonal Antibody(Capture/Detector), 25 μg

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Shelf Life:12 months

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

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Dilution:ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL

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Application:ELISA Capture/Detector

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Research Areas:Cancer;Signal transduction

Species Reactivity:Human

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Target Synonym:TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;Prolixin;Tumor Necrosis Factor Receptor Superfamily Member 13C;

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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.

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Clonality:Monoclonal

Conjugation:Unconjugated

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