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SKU: E-AB-22139_20μL-ES
BECN1 Monoclonal Antibody, 20 μL
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Observed Molecular Weight:60kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:WB 1:1000-2000;IHC 1:100-200
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Application:WB;IHC-p
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Microbiology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;Becn1;BECN1;Coiled coil myosin like BCL2 interacting protein;Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Monoclonal
Conjugation:Unconjugated
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