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SKU: E-AB-F1090B_100μg-ES
Biotin Anti-Mouse CD103 Antibody[M290], 100 μg
CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Concentration:0.5 mg/mL
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Do not freeze.
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Application:FCM
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Research Areas:Immunology
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Target Synonym:CD103;Integrin alpha M290;Integrin alpha-E;Itgae
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Clonality:Monoclonal
Conjugation:Biotin
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