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SKU: E-AB-22158_20μL-ES
c-Fos Monoclonal Antibody, 20 μL
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Observed Molecular Weight:62kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Features and Capabilities
Application:WB;IHC-p
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Activator protein 1;AP 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog;FBJ Osteosarcoma Virus;FOS;FOS protein;FOS;G0 G1 switch regulatory protein 7;G0/G1 switch regulatory protein 7;G0S7;Oncogene FOS;p55;proto oncogene c Fos;Proto oncogene protein c fos;Proto-oncogene c-Fos;v fos FBJ murine osteosarcoma viral oncogene homolog
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Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
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Clonality:Monoclonal
Conjugation:Unconjugated
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