SKU: E-AB-93363_120μL-ES

Cleaved Caspase-9 P37 Polyclonal Antibody, 120 μL

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

Capacity:

Concentration:1mg/mL

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Calculated Molecular Weight:17kDa/30kDa/36kDa/46kDa

Observed Molecular Weight:35kDa/37kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:17kDa/30kDa/36kDa/46kDa

Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200

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Features and Capabilities

Application:WB;IHC;IF

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Research Areas:Cancer;Cell Biology;Metabolism

Species Reactivity:Human;Mouse;Rat

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Target Synonym:CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;casp9;Caspase 9

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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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