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Product Specification
Brands:Beyotime
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Place of Origin:China
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Shipping:Blue Ice/Dry Ice
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Component:Endonuclease VIII (10U/µl), 10X Endonuclease VIII Buffer
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Purity:≥ 95%
Shelf Life:24 months
Storage:-20℃
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Test Principle:Beyotime’s Endonuclease VIII is a recombinant protein expressed in E. coli and purified on the PerfectProtein™ Platform developed by Beyotime. It is a DNA damage repair enzyme with both DNA N-glycosylase and AP-lyase activities. The N-glycosylase activity cuts and releases damaged pyrimidines on dsDNA to produce a Apurinic (AP) site, and the AP lyase activity cleaves DNA phosphodiester backbone at the 3' and 5' ends of the AP site, excising the AP site and creating a nucleotide DNA gap with 3' and 5' phosphate termini.
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