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SKU: E-AB-22026_20μL-ES
KIF7 Monoclonal Antibody, 20 μL
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:100-1:300;IF 1:50-200
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Application:IHC-p;IF
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Research Areas:Signal Transduction;Stem Cells
Species Reactivity:Human;Mouse;Rat
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Target Synonym:EQYK340;kif7;KIF7;kinesin family member 7;kinesin like protein KIF7;Kinesin-like protein kif7;UNQ340
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Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
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Clonality:Monoclonal
Conjugation:Unconjugated
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