SKU: E-AB-93328_60μL-ES

(KO Validated) CD33 Polyclonal Antibody, 60 μL

Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:25kDa/33kDa/39kDa

Observed Molecular Weight:67KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:25kDa/33kDa/39kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer;Immunology;Stem Cells

Species Reactivity:Human

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Target Synonym:CD33; SIGLEC-3; SIGLEC3; p67; CD33 molecule

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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