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SKU: E-AB-93317_200μL-ES
(KO Validated) p53 Polyclonal Antibody, 200 μL
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:23-43kDa
Observed Molecular Weight:53KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:23-43kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200;IP 1:50-1:200
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Application:WB;IHC;IF;IP
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling
Species Reactivity:Human
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Target Synonym:TP53; BCC7; LFS1; P53; TRP53; tumor protein p53
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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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