SKU: E-AB-22114_200μL-ES

MICU1 Monoclonal Antibody, 200 μL

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Observed Molecular Weight:55kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:WB 1:500-1:2000;IHC 1:100-1:200;IF 1:100-1:300

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Application:WB;IHC-p;IF

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Research Areas:Cancer;Metabolism;Immunology;Signal Transduction

Species Reactivity:Human;Mouse;Rat

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Target Synonym:Allergen Hom s 4;ara CALC;atopy related autoantigen;atopy related autoantigen CALC;Atopy-related autoantigen CALC;CALC;calcium binding atopy related autoantigen 1;Calcium uptake protein 1;calcium uptake protein 1;mitochondrial;Calcium-binding atopy-related autoantigen 1;CBARA1;EFHA3;FLJ12684;MICU1;MICU1;mitochondrial;mitochondrial calcium uptake 1;MPXPS

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Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

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Clonality:Monoclonal

Conjugation:Unconjugated

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