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SKU: E-AB-22148_60μL-ES
NBR1 Monoclonal Antibody, 60 μL
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-300;IF 1:50-1:200
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Application:IHC-p;IF
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Research Areas:Cancer;Cell Biology
Species Reactivity:Human;Mouse;Rat
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Target Synonym:1A1 3B;1A13B;B box protein;Cell migration-inducing gene 19 protein;KIAA0049;M17S2;Membrane component chromosome 17 surface marker 2;Membrane component;chromosome 17;surface marker 2 (ovarian carcinoma antigen CA125);MIG 19;MIG19;Migration inducing protein 19;NBR 1;Nbr1;NBR1;autophagy cargo receptor;NBR1;Neighbor of BRCA1 gene 1;Neighbor of BRCA1 gene 1 protein;Next to BRCA1 gene 1 protein;Ovarian carcinoma antigen CA125;Protein 1A1-3B
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Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
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Clonality:Monoclonal
Conjugation:Unconjugated
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