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SKU: E-AB-16658_120μL-ES
NPRL2 Polyclonal Antibody, 120 μL
NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.9 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse
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Target Synonym:2810446G01Rik;G21 protein;Gene 21 protein;Homologous to yeast nitrogen permease (candidate tumor suppressor);Homologous to yeast nitrogen permease;Nitrogen permease regulator 2-like protein;Nitrogen permease regulator-like 2 (S. cerevisiae);NPR 2L;NPR L2;NPR like 2;NPR2;NPR2 like;NPR2-like protein;NPR2L;NPRL 2;NPRL2;NPRL2;Tumor suppressor candidate 4;TUSC 4;TUSC 4 protein;TUSC4;TUSC4 protein
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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