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SKU: E-AB-22198_120μL-ES
p70 S6 kinase alpha Monoclonal Antibody, 120 μL
P70 S6 Kinase alpha is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and contains 2 non-identical kinase catalytic domains. It phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein is activated by serine/threonine phosphorylation and protein kinase C and inactivated by type 2A phosphatase. Activation leads to an increase in protein synthesis and cell proliferation. Overexpression of this kinase is involved in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:100-200
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Application:IHC-p
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:70 kDa ribosomal protein S6 kinase 1;KS6B1;p70 alpha;P70 beta 1;p70 ribosomal S6 kinase alpha;p70 ribosomal S6 kinase beta 1;p70 S6 kinase alpha;P70 S6 Kinase;p70 S6 kinase;alpha 1;p70 S6 kinase;alpha 2;p70 S6K;p70 S6K-alpha;p70 S6KA;p70(S6K) alpha;p70(S6K)-alpha;p70-alpha;p70-S6K 1;p70-S6K;P70S6K;P70S6K1;p70S6Kb;PS6K;Ribosomal protein S6 kinase 70kDa polypeptide 1;Ribosomal protein S6 kinase beta 1;Ribosomal protein S6 kinase beta-1;Ribosomal protein S6 kinase I;RPS6KB1;S6K;S6K-beta-1;S6K1;Serine/threonine kinase 14 alpha;Serine/threonine-protein kinase 14A;STK14A
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Monoclonal
Conjugation:Unconjugated
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