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SKU: E-AB-F1107D_100T-ES
PE Anti-Mouse CD115/CSF-1R Antibody[AFS98], 100 T
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Concentration:5 μL/Test
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Application:FCM
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Research Areas:Immunology
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Target Synonym:CD115;CSF-1 receptor (EC:2.7.10.1);CSF-1-R;CSF-1R;Csf1r;Csfmr;Fms;M-CSF-R;Macrophage colony-stimulating factor 1 receptor;Proto-oncogene c-Fms
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Clonality:Monoclonal
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