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SKU: E-AB-81456_50μL-ES
Recombinant ALIX Monoclonal Antibody, 50 μL
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:300 μg/mL
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Calculated Molecular Weight:96kDa
Observed Molecular Weight:96kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:96kDa
Dilution:WB 1:1000-1:2000
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Features and Capabilities
Application:WB
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Research Areas:Cell Biology; Microbiology; Signal Transduction
Species Reactivity:Human; Rat; Hamster
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Target Synonym:PDCD6IP;AIP1;ALIX;DRIP4;HP95
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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