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SKU: E-AB-81439_50μL-ES
Recombinant EGFR Monoclonal Antibody, 50 μL
EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:300 μg/mL
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Calculated Molecular Weight:134kDa
Observed Molecular Weight:175kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:134kDa
Dilution:WB 1:1000-1:2000;IF 1:50-1:200
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Application:WB;IF
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Research Areas:Cancer; Signal Transduction
Species Reactivity:Human; Mouse
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Target Synonym:Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog);Epidermal growth factor receptor;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;Errp;HER1;mENA; NISBD2;SA7;wa2;Wa5
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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