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SKU: E-AB-81446_100μL-ES
Recombinant ERK2 Monoclonal Antibody, 100 μL
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:300 μg/mL
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Calculated Molecular Weight:41kDa
Observed Molecular Weight:41kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:41kDa
Dilution:WB 1:500-1:1000;IHC 1:20-1:100;IF 1:50-1:100
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Application:WB;IHC-P
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Research Areas:Cancer; Neuroscience; Signal Transduction; Stem Cells
Species Reactivity:Human; Mouse; Rat
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Target Synonym:ERK 2;ERK;ERK-2;ERT1;Extracellular Signal Regulated Kinase 2;Extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;Mapk1;MAPK2;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;MK01;P38;P40;P41;p42-MAPK;P42MAPK;PRKM1;PRKM2;protein kinase;mitogen-activated;1;protein kinase;mitogen-activated;2;protein tyrosine kinase ERK2
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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