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SKU: AN002600P_100μg-ES
Recombinant Fas/TNFRSF6/CD95 Monoclonal Antibody(Capture), 100 μg
FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Dilution:ELISA Capture 2-8 μg/mL
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Application:ELISA Capture
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Research Areas:Cancer;Cell Biology;Immunology
Species Reactivity:Human
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Target Synonym:FASR;TNFRSF6;APO1;APT1;FAS1;FASTM;ALPS1A
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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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Clonality:Recombinant
Conjugation:Unconjugated
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