SKU: E-AB-81475_50μL-ES

Recombinant ILF3 Monoclonal Antibody, 50 μL

This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:300 μg/mL

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Calculated Molecular Weight:95kDa

Observed Molecular Weight:95kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:95kDa

Dilution:WB 1:2000-1:5000;IHC 1:50-1:100;IF 1:50-1:100

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Features and Capabilities

Application:WB;IHC-P;IF

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Research Areas:Cancer; Epigenetics and Nuclear Signaling; Signal Transduction

Species Reactivity:Human; Rat

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Target Synonym:CBTF;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;DRBF;DRBP76;ILF3;ILF3;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;MPHOSPH4;MPP4;NF AT 90;NF-AT-90;NF110;NF90;NFAR;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;TCP80;Translational control protein 80

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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

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Clonality:Rabbit Monoclonal

Conjugation:Unconjugated

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