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SKU: E-AB-81578_50μL-ES
Recombinant LC3A Monoclonal Antibody, 50 μL
LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:300 μg/mL
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Calculated Molecular Weight:14kDa
Observed Molecular Weight:16kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:14kDa
Dilution:WB 1:500-1:1000
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Application:WB
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Research Areas:Cancer; Cardiovascular; Metabolism; Signal Transduction
Species Reactivity:Human; Mouse; Rat
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Target Synonym:ATG8E;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3 like protein 1;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Map1lc3a;Microtubule associated proteins 1A/1B light chain 3;Microtubule-associated protein 1 light chain 3 alpha;Microtubule-associated proteins 1A and 1B;light chain 3;Microtubule-associated proteins 1A/1B light chain 3A;MLP3A
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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