- Specification
- Downloads
- Reviews
€386,00
ADD TO CART
SKU: PKSM041342_10μg-ES
Recombinant Mouse EDA2R/TNFRSF27 Protein (Fc Tag), 10 μg
Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA-A2 dependent apoptosis. Its transcription is directly induced by p53, and it mediated cell death is p53 dependent. it is down-regulated in breast, colon, and lung cancers, particularly in cases with p53 mutations. It also plays a role in EDA-A2 induced skeletal muscle degeneration and osteoblast differentiation. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.
- Regular price
- €386,00 EUR
- Sale price
- €386,00 EUR
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:Please refer to the printed manual for detailed information.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:42.5 kDa
Observed Molecular Weight:50-60 kDa
Purity: > 95 % as determined by reducing SDS-PAGE.
Shelf Life:
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:42.5 kDa
Dilution:
Driving Motor DC motor:
Em:
Ex:
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Flow rate [liquid]:
Features and Capabilities
Application:
Detection Target:
Detection Type:
Detection Range:
Research Areas:
Species Reactivity:
Reactivity:
Target Synonym:
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:Not validated for activity
Bottom Shape:
Bottom Type:
Buffer:
Cap Color:
Clonality:
Conjugation:
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Graduation:
Growth Area: