SKU: E-AB-81584_50μL-ES

Recombinant mtTFA Monoclonal Antibody, 50 μL

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:300 μg/mL

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Calculated Molecular Weight:29kDa

Observed Molecular Weight:24kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:29kDa

Dilution:WB 1:1000-1:2000;IHC 1:50-1:100;IF 1:50-1:100

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Application:WB;IHC-P;IF

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Research Areas:Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction; Tags and Cell Markers

Species Reactivity:Human

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Target Synonym:anscription factor 6-like 1;Mitochondrial transcription factor 1;mitochondrial transcription factor A;MtTF1;mtTFA;TCF 6;TCF-6;TCF6;TCF6L1;TCF6L2;TCF6L3;TFAM;TFAM;Transcription factor 6;Transcription factor 6 like 2 (mitochondrial transcription factor);Transcription factor 6 like 2;Transcription factor 6-like 2;transcription factor 6-like 3;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial precursor

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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

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Clonality:Rabbit Monoclonal

Conjugation:Unconjugated

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