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SKU: E-AB-81485_100μL-ES
Recombinant Semaphorin 4D Monoclonal Antibody, 100 μL
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:300 μg/mL
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Calculated Molecular Weight:96kDa
Observed Molecular Weight:120kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:96kDa
Dilution:WB 1:1000-1:5000
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Application:WB
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Research Areas:Cancer; Immunology; Neuroscience
Species Reactivity:Human
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Target Synonym:A8;BB 18;BB18;CD 100;CD100;CD100 antigen;Coll 4;COLL4;Collapsin 4;Collapsin4;GR3;Leukocyte activation antigen CD100;M sema G;MSEMA;SEM4D;Sema 4d;Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D;Sema H;SEMA J;Sema4d;Semacl 2;Semacl2;SemaH;SEMAJ;Semaphorin 4D;Semaphorin C like 2;Semaphorin H;Semaphorin J;Semaphorin-4D;Semaphorin4D;SemaphorinJ;Semcl 2;Semcl2
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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