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SKU: E-AB-67676_200μL-ES
UGT1A4 Polyclonal Antibody, 200 μL
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:49kDa/60kDa
Observed Molecular Weight:69kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:49kDa/60kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Signal Transduction; Cell Biology; Metabolism
Species Reactivity:Human; Mouse
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Target Synonym:UGT1A4;HUG-BR2;UDPGT;UDPGT 1-4;UGT-1D;UGT1-04;UGT1.4;UGT1A4S;UGT1D;UDPGT1-4
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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