SKU: AN002110P_25μg-ES

uPAR Monoclonal Antibody(Detector), 25 μg

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Shelf Life:12 months

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

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Dilution:ELISA Detector 0.1-0.4 μg/mL

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Application:ELISA Detector

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Research Areas:Cancer;Cardiovascular;Immunology

Species Reactivity:Human

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Target Synonym:CD87;U-PAR;URKR;

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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.

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Clonality:Monoclonal

Conjugation:Unconjugated

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