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SKU: E-AB-93065_120μL-ES
VDR Polyclonal Antibody, 120 μL
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:48kDa/53kDa
Observed Molecular Weight:48KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:48kDa/53kDa
Dilution:WB 1:500-1:2000;IF 1:50-1:200
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Features and Capabilities
Application:WB;IF
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal Transduction
Species Reactivity:Human;Mouse
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Target Synonym:VDR;NR1I1;PPP1R163
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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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